CRISPR, genome engineering, science policy, biotech, bioethics, 🇧🇩
graduate student researcher
National Science Foundation graduate research fellow
previous research experience
- developing new or modified CRISPR-Cas proteins using directed evolution approaches
- improving delivery of CRISPR gene editors into plant tissue
- investigating the pathways and molecular mechanisms of DNA repair
- developing engineered, cell-type specific CRISPR gene-editing reagents for in vivo delivery
- David Drubin lab – in vitro reconstitution of endocytic machinery using purified components.
- Dan Fletcher lab – characterization of de novo protein size-markers for protein-protein interactions at cell junctions.
- Susan Marqusee lab – investigating RNAse H folding dynamics using mass spectrometry and circular dichroism.
post-baccalaureate research fellow
(2014 – 2016)
National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland
principal investigator: Dr Thomas B Friedman
- studied the genetic causes for human deafness .
- purified and characterized myosin 15 proteins, mutations of which cause hearing loss.
- performed physical, kinetic, and functional studies of myosin 15.
(2012 – 2014)
Bell lab, Department of Chemistry and Biochemistry, University of Southern Mississippi
principal investigator: Dr Anthony J Bell Jr
- investigated methods of modifying DNA junctions to improve nuclease and thermal stability.
- designed and characterized hybrid DNA and synthetic nucleic acid junctions as a substrate against HMG proteins.