About Me

I am a PhD Candidate in Molecular & Cell Biology at the University of California, Berkeley.

I work at the intersection of protein engineering, genome-editing, and synthetic biology. I am a NSF Graduate Research Fellow in the Savage Lab and Innovative Genomics Institute at Berkeley. My current interests are in exploring the modularity of CRISPR-Cas proteins and protein evolution.

Welcome to my personal website.

Publications

Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
Arik Shams, Sean A. Higgins, Christof Fellmann, Thomas G. Laughlin, Benjamin L. Oakes, Rachel Lew, Maria Lukarska, Madeline Arnold, Brett Staahl, Jennifer A. Doudna, David F. Savage.
bioRxiv 2020.10.19.344077; doi: https://doi.org/10.1101/2020.10.19.344077

The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness
Fangfang Jiang, Yasuharu Takagi, Arik Shams, Sarah M. Heissler, Thomas B. Friedman, James R. Sellers, Jonathan E. Bird.
bioRxiv 2020.06.17.155424; doi: https://doi.org/10.1101/2020.06.17.155424

Characterization of the structural and protein recognition properties of hybrid PNA-DNA four-way junctions
Douglas Iverson, Crystal Serrano, Ann Marie Brahan, Arik Shams, Filbert Totsingan, Anthony J. Bell Jr.
Arch Biochem Biophys, 2015 Dec 1;587:1-11. doi: https://doi.org/10.1016/j.abb.2015.08.017. Epub 2015 Sep 5.

Education & Experience

Bachelor of Science, magna cum laude, University of Southern Mississippi
(2010 – 2014)
Biochemistry

Post-baccalaureate Research Fellow, National Institutes of Health
(2014 – 2016)
Protein biochemist at the Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, Bethesda, Maryland.

Undergraduate Researcher, University of Southern Mississippi
(2011 – 2014)
Researcher at Dr. Anthony Bell’s biochemistry lab at the University of Southern Mississippi, Hattiesburg, Mississippi.